Thromboinflammation in COVID-19 Infection

COVID-19 related coagulopathy manifesting as venous thromboembolism is now an established global phenomenon.  Clinicians can find information on this page regarding the prevention and treatment of VTE in the presence of COVID-19, as well as the effects of COVID-19 on anticoagulation.

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News:

GIRFT Thrombosis Survey Extended

Vte news main girft launch

The GIRFT Thrombosis survey represents a unique opportunity to capture national data in relation to the increase in VTE associated with the COVID-19 pandemic.  The survey has been extended to include April and May 2020.  No further data entry for part 1 (organisational) or part 2 (VTE prevention) is required.  Participants are encouraged to complete part 3, the HAT data for April and May.  The GIRFT Thrombosis portal will remain open for data entry until 31st August 2020 for this purpose.  Unfortunately, it will not be possible to extend the data entry period beyond this date.

References:

  • Chest Guidance-Prevention and treatment of VTE with COVID-19

    Moores L, Tritschler T, Brosnahan S, Carrier M, Collen J, Doerschug K, Holley AB, Jimenez D, LeGal G, Rali P, Wells P (2020) Prevention, diagnosis and treatment of venous thromboembolism in patients with COVID-19: CHEST Guideline and Expert Panel Report.

  • RCOG Guidance-COVID-19 in Pregnancy

    Royal College of Gynaecologists and Obstetricians (2020) Coronavirus (COVID-19) Infection in Pregnancy.

  • ISTH guidance-management of COVID-19 related coagulopathy

    Spyropoulos A, Levy J, Ageno W, Connors JM, Hunt B, Iba T, Levi M, Samama C, Thachil J, Giannis D, Douketis J on behalf of The ISTH (2020) Scientific and Standardization Committee Communication: Clinical Guidance on the Diagnosis, Prevention and Treatment of Venous Thromboembolism in Hospitalized Patients with COVID‐19. Journal of Thrombosis & Haemostasis

  • Thrombosis risk in COVID-19 review

    Al-Ani F, Chehade S, Lazo-Langner A (2020) Thrombosis risk associated with COVID-19 infection. A scoping review. Thrombosis Research

  • Increased warfarin sensitivity during COVID-19 pandemic

    Speed V, Patel RK, Byrne R, Roberts LN, Arya R (2020) A perfect storm: Root cause analysis of supra-therapeutic anticoagulation with vitamin K antagonists during the COVID-19 pandemic perfect. Thrombosis Research

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